Preventive and therapeutic opportunities: targeting BAP1 and/or HMGB1 pathways to diminish the burden of mesothelioma

Mesothelioma is a cancer typically caused by asbestos. Mechanistically, asbestos carcinogenesis has been linked to the asbestos-induced release of HMGB1 from the nucleus to the cytoplasm, where HMGB1 promotes autophagy and cell survival, and to the extracellular space where HMGB1 promotes chronic in...

Descripción completa

Detalles Bibliográficos
Autores principales: Carbone, Michele, Minaai, Michael, Takinishi, Yasutaka, Pagano, Ian, Yang, Haining
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599047/
https://www.ncbi.nlm.nih.gov/pubmed/37880686
http://dx.doi.org/10.1186/s12967-023-04614-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599047/
https://www.ncbi.nlm.nih.gov/pubmed/37880686
http://dx.doi.org/10.1186/s12967-023-04614-5

Ejemplares similares