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Aromatase inhibition and ketamine in rats: sex-differences in antidepressant-like efficacy
BACKGROUND: Ketamine has been recently approved to treat resistant depression; however preclinical studies showed sex differences in its efficacy. Sex steroids, such as estrogens and testosterone, both in the periphery and locally in the brain, are regarded as important modulators of these sex diffe...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599051/ https://www.ncbi.nlm.nih.gov/pubmed/37876000 http://dx.doi.org/10.1186/s13293-023-00560-5 |