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Aromatase inhibition and ketamine in rats: sex-differences in antidepressant-like efficacy

BACKGROUND: Ketamine has been recently approved to treat resistant depression; however preclinical studies showed sex differences in its efficacy. Sex steroids, such as estrogens and testosterone, both in the periphery and locally in the brain, are regarded as important modulators of these sex diffe...

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Detalles Bibliográficos
Autores principales: Ledesma-Corvi, Sandra, Jornet-Plaza, Jordi, García-Fuster, M. Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599051/
https://www.ncbi.nlm.nih.gov/pubmed/37876000
http://dx.doi.org/10.1186/s13293-023-00560-5