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Brequinar inhibits African swine fever virus replication in vitro by activating ferroptosis

BACKGROUND: African swine fever virus (ASFV) is one of the most fatal swine etiological agents and has a huge economic impact on the global pork industry. Given that no effective vaccines or anti-ASFV drugs are available, there remains a pressing need for novel anti-ASFV drugs. This study aimed to i...

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Detalles Bibliográficos
Autores principales: Chen, Yang, Guo, Yanchen, Chang, Hao, Song, Zebu, Wei, Zhi, Huang, Zhao, Zheng, Zezhong, Zhang, Guihong, Sun, Yankuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599058/
https://www.ncbi.nlm.nih.gov/pubmed/37875895
http://dx.doi.org/10.1186/s12985-023-02204-x