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Formation of the mutagenic DNA lesion 1,N(2)-ethenoguanine induced by heated cooking oil and identification of causative agents

BACKGROUND: The DNA-damaging compounds in heated cooking oil were identified as guanosine adducts. Heated vegetable oil was subjected to deep-frying conditions at 170 °C for 45 min, reacted with isopropylidene guanosine (ipG) at pH 7.4, and the resulting compounds were separated by high-performance...

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Detalles Bibliográficos
Autores principales: Kasai, Hiroshi, Kawai, Kazuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599067/
https://www.ncbi.nlm.nih.gov/pubmed/37880746
http://dx.doi.org/10.1186/s41021-023-00284-3