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Piperlongumine induces apoptosis via the MAPK pathway and ERK-mediated autophagy in human melanoma cells

Piperlongumine (PL) is an amide alkaloid with diverse pharmacological effects against cancer, bronchitis and asthma; however, research on its efficacy against melanoma is lacking. The present study investigated the anticancer effects of PL on A375SM and A375P human melanoma cells. PL decreased the s...

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Detalles Bibliográficos
Autores principales: Jeon, Su-Ji, Choi, Eun-Young, Han, Eun-Ji, Lee, Sang-Woo, Moon, Jun-Mo, Jung, Soo-Hyun, Jung, Ji-Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599349/
https://www.ncbi.nlm.nih.gov/pubmed/37830157
http://dx.doi.org/10.3892/ijmm.2023.5318