The role of branched-chain aminotransferase 1 in driving glioblastoma cell proliferation and invasion varies with tumor subtype

BACKGROUND: Branched-chain aminotransferase 1 (BCAT1) has been proposed to drive proliferation and invasion of isocitrate dehydrogenase (IDH) wild-type glioblastoma cells. However, the Cancer Genome Atlas (TCGA) dataset shows considerable variation in the expression of this enzyme in glioblastoma. T...

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Detalles Bibliográficos
Autores principales: Fala, Maria, Ros, Susana, Sawle, Ashley, Rao, Jyotsna U, Tsyben, Anastasia, Tronci, Laura, Frezza, Christian, Mair, Richard, Brindle, Kevin M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599397/
https://www.ncbi.nlm.nih.gov/pubmed/37885806
http://dx.doi.org/10.1093/noajnl/vdad120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599397/
https://www.ncbi.nlm.nih.gov/pubmed/37885806
http://dx.doi.org/10.1093/noajnl/vdad120

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