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Synergistically remodulating H(+)/Ca(2+) gradients to induce mitochondrial depolarization for enhanced synergistic cancer therapy

The remodulation of H(+)/Ca(2+) gradients in the mitochondria matrix could be effective to induce mitochondria depolarization for the enhancement of cancer therapy. However, it is still challenged by H(+) homeostasis, insufficient Ca(2+), uncoordinated regulations, and inefficient loading/delivery s...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoni, Ge, Xiyang, Guan, Xiaowen, Ouyang, Jin, Na, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599464/
https://www.ncbi.nlm.nih.gov/pubmed/37886105
http://dx.doi.org/10.1039/d3sc03493c