Cyclobutane-bearing restricted anchoring residues enabled geometry-specific hydrocarbon peptide stapling

Stapled peptides are regarded as the promising next-generation therapeutics because of their improved secondary structure, membrane permeability and metabolic stability as compared with the prototype linear peptides. Usually, stapled peptides are obtained by a hydrocarbon stapling technique, anchori...

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Detalles Bibliográficos
Autores principales: Chen, Baobao, Liu, Chao, Cong, Wei, Gao, Fei, Zou, Yan, Su, Li, Liu, Lei, Hillisch, Alexander, Lehmann, Lutz, Bierer, Donald, Li, Xiang, Hu, Hong-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599482/
https://www.ncbi.nlm.nih.gov/pubmed/37886087
http://dx.doi.org/10.1039/d3sc04279k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599482/
https://www.ncbi.nlm.nih.gov/pubmed/37886087
http://dx.doi.org/10.1039/d3sc04279k

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