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GPC-100, a novel CXCR4 antagonist, improves in vivo hematopoietic cell mobilization when combined with propranolol

Autologous Stem Cell Transplant (ASCT) is increasingly used to treat hematological malignancies. A key requisite for ASCT is mobilization of hematopoietic stem cells into peripheral blood, where they are collected by apheresis and stored for later transplantation. However, success is often hindered...

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Detalles Bibliográficos
Autores principales: Sukhtankar, Devki D., Fung, Juan José, Kim, Mi-na, Cayton, Thomas, Chiou, Valerie, Caculitan, Niña G., Zalicki, Piotr, Kim, Sujeong, Jo, Yoonjung, Kim, SoHui, Lee, Jae Min, Choi, Junhee, Mun, SeongGyeong, Chin, Ashley, Jang, Yongdae, Lee, Ji Yeong, Kim, Gowoon, Kim, Eun Hee, Huh, Won-Ki, Jeong, Jae-Yeon, Seen, Dong-Seung, Cardarelli, Pina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599528/
https://www.ncbi.nlm.nih.gov/pubmed/37878624
http://dx.doi.org/10.1371/journal.pone.0287863