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Temperature sensitive contact modes allosterically gate TRPV3

TRPV Ion channels are sophisticated molecular sensors designed to respond to distinct temperature thresholds. The recent surge in cryo-EM structures has provided numerous insights into the structural rearrangements accompanying their opening and closing; however, the molecular mechanisms by which TR...

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Detalles Bibliográficos
Autores principales: Burns, Daniel, Venditti, Vincenzo, Potoyan, Davit A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599574/
https://www.ncbi.nlm.nih.gov/pubmed/37831724
http://dx.doi.org/10.1371/journal.pcbi.1011545