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Nucleus-independent transgenerational small RNA inheritance in Caenorhabditis elegans

In Caenorhabditis elegans worms, epigenetic information transmits transgenerationally. Still, it is unknown whether the effects transfer to the next generation inside or outside of the nucleus. Here, we use the tractability of gene-specific double-stranded RNA–induced silencing to demonstrate that R...

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Detalles Bibliográficos
Autores principales: Rieger, Itai, Weintraub, Guy, Lev, Itamar, Goldstein, Kesem, Bar-Zvi, Dana, Anava, Sarit, Gingold, Hila, Shaham, Shai, Rechavi, Oded
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599617/
https://www.ncbi.nlm.nih.gov/pubmed/37878696
http://dx.doi.org/10.1126/sciadv.adj8618