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A multifunctional soft robot for cardiac interventions

In minimally invasive endovascular procedures, surgeons rely on catheters with low dexterity and high aspect ratios to reach an anatomical target. However, the environment inside the beating heart presents a combination of challenges unique to few anatomic locations, making it difficult for interven...

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Autores principales: Rogatinsky, Jacob, Recco, Dominic, Feichtmeier, Joseph, Kang, Yuchen, Kneier, Nicholas, Hammer, Peter, O’Leary, Edward, Mah, Douglas, Hoganson, David, Vasilyev, Nikolay V., Ranzani, Tommaso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599628/
https://www.ncbi.nlm.nih.gov/pubmed/37878705
http://dx.doi.org/10.1126/sciadv.adi5559
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author Rogatinsky, Jacob
Recco, Dominic
Feichtmeier, Joseph
Kang, Yuchen
Kneier, Nicholas
Hammer, Peter
O’Leary, Edward
Mah, Douglas
Hoganson, David
Vasilyev, Nikolay V.
Ranzani, Tommaso
author_facet Rogatinsky, Jacob
Recco, Dominic
Feichtmeier, Joseph
Kang, Yuchen
Kneier, Nicholas
Hammer, Peter
O’Leary, Edward
Mah, Douglas
Hoganson, David
Vasilyev, Nikolay V.
Ranzani, Tommaso
author_sort Rogatinsky, Jacob
collection PubMed
description In minimally invasive endovascular procedures, surgeons rely on catheters with low dexterity and high aspect ratios to reach an anatomical target. However, the environment inside the beating heart presents a combination of challenges unique to few anatomic locations, making it difficult for interventional tools to maneuver dexterously and apply substantial forces on an intracardiac target. We demonstrate a millimeter-scale soft robotic platform that can deploy and self-stabilize at the entrance to the heart, and guide existing interventional tools toward a target site. In two exemplar intracardiac procedures within the right atrium, the robotic platform provides enough dexterity to reach multiple anatomical targets, enough stability to maintain constant contact on motile targets, and enough mechanical leverage to generate newton-level forces. Because the device addresses ongoing challenges in minimally invasive intracardiac intervention, it may enable the further development of catheter-based interventions.
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spelling pubmed-105996282023-10-26 A multifunctional soft robot for cardiac interventions Rogatinsky, Jacob Recco, Dominic Feichtmeier, Joseph Kang, Yuchen Kneier, Nicholas Hammer, Peter O’Leary, Edward Mah, Douglas Hoganson, David Vasilyev, Nikolay V. Ranzani, Tommaso Sci Adv Physical and Materials Sciences In minimally invasive endovascular procedures, surgeons rely on catheters with low dexterity and high aspect ratios to reach an anatomical target. However, the environment inside the beating heart presents a combination of challenges unique to few anatomic locations, making it difficult for interventional tools to maneuver dexterously and apply substantial forces on an intracardiac target. We demonstrate a millimeter-scale soft robotic platform that can deploy and self-stabilize at the entrance to the heart, and guide existing interventional tools toward a target site. In two exemplar intracardiac procedures within the right atrium, the robotic platform provides enough dexterity to reach multiple anatomical targets, enough stability to maintain constant contact on motile targets, and enough mechanical leverage to generate newton-level forces. Because the device addresses ongoing challenges in minimally invasive intracardiac intervention, it may enable the further development of catheter-based interventions. American Association for the Advancement of Science 2023-10-25 /pmc/articles/PMC10599628/ /pubmed/37878705 http://dx.doi.org/10.1126/sciadv.adi5559 Text en Copyright © 2023 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY). https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Physical and Materials Sciences
Rogatinsky, Jacob
Recco, Dominic
Feichtmeier, Joseph
Kang, Yuchen
Kneier, Nicholas
Hammer, Peter
O’Leary, Edward
Mah, Douglas
Hoganson, David
Vasilyev, Nikolay V.
Ranzani, Tommaso
A multifunctional soft robot for cardiac interventions
title A multifunctional soft robot for cardiac interventions
title_full A multifunctional soft robot for cardiac interventions
title_fullStr A multifunctional soft robot for cardiac interventions
title_full_unstemmed A multifunctional soft robot for cardiac interventions
title_short A multifunctional soft robot for cardiac interventions
title_sort multifunctional soft robot for cardiac interventions
topic Physical and Materials Sciences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599628/
https://www.ncbi.nlm.nih.gov/pubmed/37878705
http://dx.doi.org/10.1126/sciadv.adi5559
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