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Neuronal HLH-30/TFEB modulates thermoresistance and longevity in C. elegans

The conserved autophagy transcription factor HLH-30/TFEB is a well-established modulator of lifespan in several mechanistically-distinct longevity paradigms in C. elegans. While various tissues contribute differentially to organismal lifespan, neurons are particularly interesting as they can mediate...

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Detalles Bibliográficos
Autor principal: Lapierre, Louis R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599725/
https://www.ncbi.nlm.nih.gov/pubmed/37837476
http://dx.doi.org/10.18632/aging.204849