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BMAL1 modulates senescence programming via AP-1

Cellular senescence and circadian dysregulation are biological hallmarks of aging. Whether they are coordinately regulated has not been thoroughly studied. We hypothesize that BMAL1, a pioneer transcription factor and master regulator of the molecular circadian clock, plays a role in the senescence...

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Detalles Bibliográficos
Autores principales: Jachim, Sarah K., Zhong, Jian, Ordog, Tamas, Lee, Jeong-Heon, Bhagwate, Aditya V., Nagaraj, Nagaswaroop Kengunte, Westendorf, Jennifer J., Passos, João F., Matveyenko, Aleksey V., LeBrasseur, Nathan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599731/
https://www.ncbi.nlm.nih.gov/pubmed/37819791
http://dx.doi.org/10.18632/aging.205112