Modified iPOND revealed the role of mutant p53 in promoting helicase function and telomere maintenance

The G-rich DNA, such as telomere, tends to form G-quadruplex (G4) structure, which slows down the replication fork progression, induces replication stress, and becomes the chromosome fragile sites. Here we described a molecular strategy that cells developed to overcome the DNA replication stress via...

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Detalles Bibliográficos
Autores principales: Wang, Qianqian, Hou, Kailong, Yang, Jun, Li, Haili, Li, Cui, Zhang, Yanduo, Tian, Jie, Li, Chuanbiao, Guo, Bing, Jia, Shuting, Luo, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599736/
https://www.ncbi.nlm.nih.gov/pubmed/37827695
http://dx.doi.org/10.18632/aging.205117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599736/
https://www.ncbi.nlm.nih.gov/pubmed/37827695
http://dx.doi.org/10.18632/aging.205117

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