Reduction of double-strand DNA break repair exacerbates vascular aging

Advanced age is the greatest risk factor for cardiovascular disease (CVD), the leading cause of death. Arterial function is impaired in advanced age which contributes to the development of CVD. One underexplored hypothesis is that DNA damage within arteries leads to this dysfunction, yet evidence de...

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Detalles Bibliográficos
Autores principales: Bloom, Samuel I., Tucker, Jordan R., Machin, Daniel R., Abdeahad, Hossein, Adeyemo, AdeLola O., Thomas, Tyler G., Bramwell, R. Colton, Lesniewski, Lisa A., Donato, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599741/
https://www.ncbi.nlm.nih.gov/pubmed/37787989
http://dx.doi.org/10.18632/aging.205066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599741/
https://www.ncbi.nlm.nih.gov/pubmed/37787989
http://dx.doi.org/10.18632/aging.205066

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