Dendrobium officinale polysaccharide decreases podocyte injury in diabetic nephropathy by regulating IRS-1/AKT signal and promoting mitophagy

Backgrounds: High glucose (HG) caused oxidative stress and mitochondrial dysfunction, resulting in insulin resistance in podocytes, a key mechanism of diabetic nephropathy. Dendrobium officinale polysaccharide (DOP) was able to improve insulin resistance and antioxidant capability. Objective: The pu...

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Detalles Bibliográficos
Autores principales: Li, Huahua, Zheng, Jin, Wu, Yacen, Zhou, Hong, Zeng, Suli, Li, Quanqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599763/
https://www.ncbi.nlm.nih.gov/pubmed/37812195
http://dx.doi.org/10.18632/aging.205075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599763/
https://www.ncbi.nlm.nih.gov/pubmed/37812195
http://dx.doi.org/10.18632/aging.205075

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