Antiviral type III CRISPR signalling via conjugation of ATP and SAM

CRISPR systems are widespread in the prokaryotic world, providing adaptive immunity against mobile genetic elements(1,2). Type III CRISPR systems, with the signature gene cas10, use CRISPR RNA to detect non-self RNA, activating the enzymatic Cas10 subunit to defend the cell against mobile genetic el...

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Detalles Bibliográficos
Autores principales: Chi, Haotian, Hoikkala, Ville, Grüschow, Sabine, Graham, Shirley, Shirran, Sally, White, Malcolm F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600005/
https://www.ncbi.nlm.nih.gov/pubmed/37853119
http://dx.doi.org/10.1038/s41586-023-06620-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600005/
https://www.ncbi.nlm.nih.gov/pubmed/37853119
http://dx.doi.org/10.1038/s41586-023-06620-5

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