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Antiviral type III CRISPR signalling via conjugation of ATP and SAM
CRISPR systems are widespread in the prokaryotic world, providing adaptive immunity against mobile genetic elements(1,2). Type III CRISPR systems, with the signature gene cas10, use CRISPR RNA to detect non-self RNA, activating the enzymatic Cas10 subunit to defend the cell against mobile genetic el...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600005/ https://www.ncbi.nlm.nih.gov/pubmed/37853119 http://dx.doi.org/10.1038/s41586-023-06620-5 |