Sustained antidepressant effect of ketamine through NMDAR trapping in the LHb

Ketamine, an N-methyl-d-aspartate receptor (NMDAR) antagonist(1), has revolutionized the treatment of depression because of its potent, rapid and sustained antidepressant effects(2–4). Although the elimination half-life of ketamine is only 13 min in mice(5), its antidepressant activities can last fo...

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Detalles Bibliográficos
Autores principales: Ma, Shuangshuang, Chen, Min, Jiang, Yihao, Xiang, Xinkuan, Wang, Shiqi, Wu, Zuohang, Li, Shuo, Cui, Yihui, Wang, Junying, Zhu, Yanqing, Zhang, Yan, Ma, Huan, Duan, Shumin, Li, Haohong, Yang, Yan, Lingle, Christopher J., Hu, Hailan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600008/
https://www.ncbi.nlm.nih.gov/pubmed/37853123
http://dx.doi.org/10.1038/s41586-023-06624-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600008/
https://www.ncbi.nlm.nih.gov/pubmed/37853123
http://dx.doi.org/10.1038/s41586-023-06624-1

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