Lenvatinib activates anti-tumor immunity by suppressing immunoinhibitory infiltrates in the tumor microenvironment of advanced hepatocellular carcinoma

BACKGROUND: Lenvatinib, a multiple receptor tyrosine kinase inhibitor, might exert antitumor effects via tumor immune modulation. However, changes in the tumor immune microenvironment induced by lenvatinib are poorly understood. We investigated the effect of lenvatinib on immune features in clinical...

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Detalles Bibliográficos
Autores principales: Yamauchi, Masami, Ono, Atsushi, Amioka, Kei, Fujii, Yasutoshi, Nakahara, Hikaru, Teraoka, Yuji, Uchikawa, Shinsuke, Fujino, Hatsue, Nakahara, Takashi, Murakami, Eisuke, Okamoto, Wataru, Miki, Daiki, Kawaoka, Tomokazu, Tsuge, Masataka, Imamura, Michio, Hayes, C. Nelson, Ohishi, Waka, Kishi, Takeshi, Kimura, Mizuki, Suzuki, Natsumi, Arihiro, Koji, Aikata, Hiroshi, Chayama, Kazuaki, Oka, Shiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600115/
https://www.ncbi.nlm.nih.gov/pubmed/37880538
http://dx.doi.org/10.1038/s43856-023-00390-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600115/
https://www.ncbi.nlm.nih.gov/pubmed/37880538
http://dx.doi.org/10.1038/s43856-023-00390-x

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