Cargando…

PPARα activation promotes liver progenitor cell-mediated liver regeneration by suppressing YAP signaling in zebrafish

Despite the robust regenerative capacity of the liver, prolonged and severe liver damage impairs liver regeneration, leading to liver failure. Since the liver co-opts the differentiation of liver progenitor cells (LPCs) into hepatocytes to restore functional hepatocytes, augmenting LPC-mediated live...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Minwook, So, Juhoon, Shin, Donghun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600117/
https://www.ncbi.nlm.nih.gov/pubmed/37880271
http://dx.doi.org/10.1038/s41598-023-44935-5