Hidden prevalence of deletion-inversion bi-alleles in CRISPR-mediated deletions of tandemly arrayed genes in plants

Tandemly arrayed genes (TAGs) with functional redundancy and chromosomal linkage constitute 14 ~ 35% in sequenced plant genomes. The multiplex CRISPR system is the tool of choice for creating targeted TAG deletions. Here, we show that up to ~80% of CRISPR-mediated TAG knockout alleles in Arabidopsis...

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Detalles Bibliográficos
Autores principales: Liu, Jiuer, Wang, Feng-Zhu, Li, Chong, Li, Yujia, Li, Jian-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600118/
https://www.ncbi.nlm.nih.gov/pubmed/37880225
http://dx.doi.org/10.1038/s41467-023-42490-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600118/
https://www.ncbi.nlm.nih.gov/pubmed/37880225
http://dx.doi.org/10.1038/s41467-023-42490-1

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