Cigarette smoke causes a bioenergetic crisis in RPE cells involving the downregulation of HIF-1α under normoxia

Age-related macular degeneration (AMD) is the most common blinding disease in the elderly population. However, there are still many uncertainties regarding the pathophysiology at the molecular level. Currently, impaired energy metabolism in retinal pigment epithelium (RPE) cells is discussed as one...

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Detalles Bibliográficos
Autores principales: Henning, Yoshiyuki, Willbrand, Katrin, Larafa, Safa, Weißenberg, Gesa, Matschke, Veronika, Theiss, Carsten, Görtz, Gina-Eva, Matschke, Johann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600121/
https://www.ncbi.nlm.nih.gov/pubmed/37880219
http://dx.doi.org/10.1038/s41420-023-01695-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600121/
https://www.ncbi.nlm.nih.gov/pubmed/37880219
http://dx.doi.org/10.1038/s41420-023-01695-5

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