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The GPCR adaptor protein Norbin regulates S1PR1 trafficking and the morphology, cell cycle and survival of PC12 cells

Norbin is an adaptor protein that binds numerous G protein-coupled receptors (GPCRs), is highly expressed in neurons, and is essential for a functioning nervous system in rodent models. Yet, beyond its control of neurite outgrowth and synaptic plasticity, few cellular roles of Norbin have been inves...

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Detalles Bibliográficos
Autores principales: Johansen, Valdemar B. I., Hampson, Elizabeth, Tsonou, Elpida, Pantarelli, Chiara, Chu, Julia Y., Crossland, Laraine, Okkenhaug, Hanneke, Massey, Andrew J., Hornigold, David C., Welch, Heidi C. E., Chetwynd, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600135/
https://www.ncbi.nlm.nih.gov/pubmed/37880240
http://dx.doi.org/10.1038/s41598-023-45148-6