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Microglial cannabinoid receptor type 1 mediates social memory deficits in mice produced by adolescent THC exposure and 16p11.2 duplication
Adolescent cannabis use increases the risk for cognitive impairments and psychiatric disorders. Cannabinoid receptor type 1 (Cnr1) is expressed not only in neurons and astrocytes, but also in microglia, which shape synaptic connections during adolescence. However, the role of microglia in mediating...
Autores principales: | Hasegawa, Yuto, Kim, Juhyun, Ursini, Gianluca, Jouroukhin, Yan, Zhu, Xiaolei, Miyahara, Yu, Xiong, Feiyi, Madireddy, Samskruthi, Obayashi, Mizuho, Lutz, Beat, Sawa, Akira, Brown, Solange P., Pletnikov, Mikhail V., Kamiya, Atsushi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600150/ https://www.ncbi.nlm.nih.gov/pubmed/37880248 http://dx.doi.org/10.1038/s41467-023-42276-5 |
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