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Downregulation of mGluR1-mediated signaling underlying autistic-like core symptoms in Shank1 P1812L-knock-in mice

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by core symptoms that consist of social deficits and repetitive behaviors. Unfortunately, no effective medication is available thus far to target the core symptoms of ASD, since the pathogenesis remains largely unknown. To...

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Detalles Bibliográficos
Autores principales: Qin, Yue, Zhang, Xiao-Yong, Liu, Yanyan, Ma, Zehan, Tao, Shuo, Li, Ying, Peng, Rui, Wang, Fei, Wang, Jiucun, Feng, Jianfeng, Qiu, Zilong, Jin, Li, Wang, Hongyan, Gong, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600164/
https://www.ncbi.nlm.nih.gov/pubmed/37880287
http://dx.doi.org/10.1038/s41398-023-02626-9