Cargando…
Downregulation of mGluR1-mediated signaling underlying autistic-like core symptoms in Shank1 P1812L-knock-in mice
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by core symptoms that consist of social deficits and repetitive behaviors. Unfortunately, no effective medication is available thus far to target the core symptoms of ASD, since the pathogenesis remains largely unknown. To...
Autores principales: | Qin, Yue, Zhang, Xiao-Yong, Liu, Yanyan, Ma, Zehan, Tao, Shuo, Li, Ying, Peng, Rui, Wang, Fei, Wang, Jiucun, Feng, Jianfeng, Qiu, Zilong, Jin, Li, Wang, Hongyan, Gong, Xiaohong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600164/ https://www.ncbi.nlm.nih.gov/pubmed/37880287 http://dx.doi.org/10.1038/s41398-023-02626-9 |
Ejemplares similares
-
A recurrent SHANK1 mutation implicated in autism spectrum disorder causes autistic-like core behaviors in mice via downregulation of mGluR1-IP3R1-calcium signaling
por: Qin, Yue, et al.
Publicado: (2022) -
Correction: A recurrent SHANK1 mutation implicated in autism spectrum disorder causes autistic-like core behaviors in mice via downregulation of mGluR1-IP3R1-calcium signaling
por: Qin, Yue, et al.
Publicado: (2022) -
Overexpression of mGluR7 in the Prefrontal Cortex Attenuates Autistic Behaviors in Mice
por: Wang, Xiaona, et al.
Publicado: (2021) -
Hyperactivity and Hypermotivation Associated With Increased Striatal mGluR1 Signaling in a Shank2 Rat Model of Autism
por: Modi, Meera E., et al.
Publicado: (2018) -
Corrigendum: Overexpression of mGluR7 in the Prefrontal Cortex Attenuates Autistic Behaviors in Mice
por: Wang, Xiaona, et al.
Publicado: (2021)