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KDM5 family of demethylases promotes CD44-mediated chemoresistance in pancreatic adenocarcinomas

A growing body of evidence suggests that the histone demethylase-lysine demethylase 5 (KDM5) family is associated with drug resistance in cancer cells. However, it is still not clear whether KDM5 family members promote chemotherapy resistance in pancreatic ductal adenocarcinomas (PDAC). Comprehensiv...

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Detalles Bibliográficos
Autores principales: Wang, Dan, Zhang, Yingjun, Liao, Zhouning, Ge, Heming, Güngör, Cenap, Li, Yuqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600175/
https://www.ncbi.nlm.nih.gov/pubmed/37880235
http://dx.doi.org/10.1038/s41598-023-44536-2