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Localized cardiac small molecule trajectories and persistent chemical sequelae in experimental Chagas disease

Post-infectious conditions present major health burdens but remain poorly understood. In Chagas disease (CD), caused by Trypanosoma cruzi parasites, antiparasitic agents that successfully clear T. cruzi do not always improve clinical outcomes. In this study, we reveal differential small molecule tra...

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Detalles Bibliográficos
Autores principales: Liu, Zongyuan, Ulrich vonBargen, Rebecca, Kendricks, April L., Wheeler, Kate, Leão, Ana Carolina, Sankaranarayanan, Krithivasan, Dean, Danya A., Kane, Shelley S., Hossain, Ekram, Pollet, Jeroen, Bottazzi, Maria Elena, Hotez, Peter J., Jones, Kathryn M., McCall, Laura-Isobel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600178/
https://www.ncbi.nlm.nih.gov/pubmed/37880260
http://dx.doi.org/10.1038/s41467-023-42247-w