New insights in the targets of action of dimethyl fumarate in endothelial cells: effects on energetic metabolism and serine synthesis in vitro and in vivo

Dimethyl fumarate is an ester from the Krebs cycle intermediate fumarate. This drug is approved and currently used for the treatment of psoriasis and multiple sclerosis, and its anti-angiogenic activity was reported some years ago. Due to the current clinical relevance of this compound and the recen...

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Detalles Bibliográficos
Autores principales: Ocaña, Mª Carmen, Bernal, Manuel, Yang, Chendong, Caro, Carlos, Domínguez, Alejandro, Vu, Hieu S., Cárdenas, Casimiro, García-Martín, María Luisa, DeBerardinis, Ralph J., Quesada, Ana R., Martínez-Poveda, Beatriz, Medina, Miguel Ángel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600195/
https://www.ncbi.nlm.nih.gov/pubmed/37880317
http://dx.doi.org/10.1038/s42003-023-05443-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600195/
https://www.ncbi.nlm.nih.gov/pubmed/37880317
http://dx.doi.org/10.1038/s42003-023-05443-4

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