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Lamin A upregulation reorganizes the genome during rod photoreceptor degeneration

Neurodegenerative diseases are accompanied by dynamic changes in gene expression, including the upregulation of hallmark stress-responsive genes. While the transcriptional pathways that impart adaptive and maladaptive gene expression signatures have been the focus of intense study, the role of highe...

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Detalles Bibliográficos
Autores principales: Herrera, Ivana, Fernandes, José Alex Lourenço, Shir-Mohammadi, Khatereh, Levesque, Jasmine, Mattar, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600220/
https://www.ncbi.nlm.nih.gov/pubmed/37880237
http://dx.doi.org/10.1038/s41419-023-06224-x