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Lamin A upregulation reorganizes the genome during rod photoreceptor degeneration
Neurodegenerative diseases are accompanied by dynamic changes in gene expression, including the upregulation of hallmark stress-responsive genes. While the transcriptional pathways that impart adaptive and maladaptive gene expression signatures have been the focus of intense study, the role of highe...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600220/ https://www.ncbi.nlm.nih.gov/pubmed/37880237 http://dx.doi.org/10.1038/s41419-023-06224-x |