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Chromatin accessibility landscape of relapsed pediatric B-lineage acute lymphoblastic leukemia

For around half of the pediatric B-lineage acute lymphoblastic leukemia (B-ALL) patients, the molecular mechanism of relapse remains unclear. To fill this gap in knowledge, here we characterize the chromatin accessibility landscape in pediatric relapsed B-ALL. We observe rewired accessible chromatin...

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Detalles Bibliográficos
Autores principales: Wang, Han, Sun, Huiying, Liang, Bilin, Zhang, Fang, Yang, Fan, Cui, Bowen, Ding, Lixia, Wang, Xiang, Wang, Ronghua, Cai, Jiaoyang, Tang, Yanjing, Rao, Jianan, Hu, Wenting, Zhao, Shuang, Wu, Wenyan, Chen, Xiaoxiao, Wu, Kefei, Lai, Junchen, Xie, Yangyang, Li, Benshang, Tang, Jingyan, Shen, Shuhong, Liu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600232/
https://www.ncbi.nlm.nih.gov/pubmed/37880218
http://dx.doi.org/10.1038/s41467-023-42565-z