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Organoids transplantation attenuates intestinal ischemia/reperfusion injury in mice through L-Malic acid-mediated M2 macrophage polarization

Intestinal organoid transplantation is a promising therapy for the treatment of mucosal injury. However, how the transplanted organoids regulate the immune microenvironment of recipient mice and their role in treating intestinal ischemia-reperfusion (I/R) injury remains unclear. Here, we establish a...

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Detalles Bibliográficos
Autores principales: Zhang, Fang-Ling, Hu, Zhen, Wang, Yi-Fan, Zhang, Wen-Juan, Zhou, Bo-Wei, Sun, Qi-Shun, Lin, Ze-Bin, Liu, Ke-Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600233/
https://www.ncbi.nlm.nih.gov/pubmed/37880227
http://dx.doi.org/10.1038/s41467-023-42502-0