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Impact of C- and N-terminal protection on the stability, metal chelation and antimicrobial properties of calcitermin

The main limitation to the use of antimicrobial peptides (AMPs) as regular drugs, against antibiotic and antifungal resistance, mainly relates to their rapid degradation by proteolytic enzymes. The introduction of suitable structural changes in the peptide chain can make the peptide less susceptible...

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Detalles Bibliográficos
Autores principales: D’Accolti, Maria, Bellotti, Denise, Dzień, Emilia, Leonetti, Carlotta, Leveraro, Silvia, Albanese, Valentina, Marzola, Erika, Guerrini, Remo, Caselli, Elisabetta, Rowińska-Żyrek, Magdalena, Remelli, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600247/
https://www.ncbi.nlm.nih.gov/pubmed/37880318
http://dx.doi.org/10.1038/s41598-023-45437-0