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Impact of C- and N-terminal protection on the stability, metal chelation and antimicrobial properties of calcitermin
The main limitation to the use of antimicrobial peptides (AMPs) as regular drugs, against antibiotic and antifungal resistance, mainly relates to their rapid degradation by proteolytic enzymes. The introduction of suitable structural changes in the peptide chain can make the peptide less susceptible...
Autores principales: | D’Accolti, Maria, Bellotti, Denise, Dzień, Emilia, Leonetti, Carlotta, Leveraro, Silvia, Albanese, Valentina, Marzola, Erika, Guerrini, Remo, Caselli, Elisabetta, Rowińska-Żyrek, Magdalena, Remelli, Maurizio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600247/ https://www.ncbi.nlm.nih.gov/pubmed/37880318 http://dx.doi.org/10.1038/s41598-023-45437-0 |
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