Neuron-secreted NLGN3 ameliorates ischemic brain injury via activating Gαi1/3-Akt signaling

We here tested the potential activity and the underlying mechanisms of neuroligin-3 (NLGN3) against ischemia-reperfusion-induced neuronal cell injury. In SH-SY5Y neuronal cells and primary murine cortical neurons, NLGN3 activated Akt-mTOR and Erk signalings, and inhibited oxygen and glucose deprivat...

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Detalles Bibliográficos
Autores principales: Chen, Zhi-guo, Shi, Xin, Zhang, Xian-xian, Yang, Fang-Fang, Li, Ke-ran, Fang, Qi, Cao, Cong, Chen, Xiong-hui, Peng, Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600254/
https://www.ncbi.nlm.nih.gov/pubmed/37880221
http://dx.doi.org/10.1038/s41419-023-06219-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600254/
https://www.ncbi.nlm.nih.gov/pubmed/37880221
http://dx.doi.org/10.1038/s41419-023-06219-8

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