Accelerating the in vitro emulation of Alzheimer’s disease-associated phenotypes using a novel 3D blood-brain barrier neurosphere co-culture model

High failure rates in clinical trials for neurodegenerative disorders such as Alzheimer’s disease have been linked to an insufficient predictive validity of current animal-based disease models. This has created an increasing demand for alternative, human-based models capable of emulating key patholo...

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Detalles Bibliográficos
Autores principales: Ko, Eunkyung Clare, Spitz, Sarah, Pramotton, Francesca Michela, Barr, Olivia M., Xu, Ciana, Pavlou, Georgios, Zhang, Shun, Tsai, Alice, Maaser-Hecker, Anna, Jorfi, Mehdi, Choi, Se Hoon, Tanzi, Rudolph E., Kamm, Roger D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600382/
https://www.ncbi.nlm.nih.gov/pubmed/37901842
http://dx.doi.org/10.3389/fbioe.2023.1251195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600382/
https://www.ncbi.nlm.nih.gov/pubmed/37901842
http://dx.doi.org/10.3389/fbioe.2023.1251195

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