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Insights from the protein interaction Universe of the multifunctional “Goldilocks” kinase DYRK1A

Human Dual specificity tyrosine (Y)-Regulated Kinase 1A (DYRK1A) is encoded by a dosage-dependent gene located in the Down syndrome critical region of human chromosome 21. The known substrates of DYRK1A include proteins involved in transcription, cell cycle control, DNA repair and other processes. H...

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Detalles Bibliográficos
Autores principales: Ananthapadmanabhan, Varsha, Shows, Kathryn H., Dickinson, Amanda J., Litovchick, Larisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600473/
https://www.ncbi.nlm.nih.gov/pubmed/37900285
http://dx.doi.org/10.3389/fcell.2023.1277537