Cargando…
Insights from the protein interaction Universe of the multifunctional “Goldilocks” kinase DYRK1A
Human Dual specificity tyrosine (Y)-Regulated Kinase 1A (DYRK1A) is encoded by a dosage-dependent gene located in the Down syndrome critical region of human chromosome 21. The known substrates of DYRK1A include proteins involved in transcription, cell cycle control, DNA repair and other processes. H...
Autores principales: | Ananthapadmanabhan, Varsha, Shows, Kathryn H., Dickinson, Amanda J., Litovchick, Larisa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600473/ https://www.ncbi.nlm.nih.gov/pubmed/37900285 http://dx.doi.org/10.3389/fcell.2023.1277537 |
Ejemplares similares
-
DYRK1A regulates the recruitment of 53BP1 to the sites of DNA damage in part through interaction with RNF169
por: R. Menon, Vijay, et al.
Publicado: (2019) -
CIRBP Knockdown Attenuates Tumourigenesis and Improves the Chemosensitivity of Pancreatic Cancer via the Downregulation of DYRK1B
por: Chen, Xiang, et al.
Publicado: (2021) -
Editorial: Novel Insights Into the Multifaceted Mitotic Kinases
por: Elowe, Sabine
Publicado: (2019) -
Multiple Forms of Multifunctional Proteins in Health and Disease
por: Espinosa-Cantú, Adriana, et al.
Publicado: (2020) -
The novel ciliogenesis regulator DYRK2 governs Hedgehog signaling during mouse embryogenesis
por: Yoshida, Saishu, et al.
Publicado: (2020)