Hypercapnia increases ACE2 expression and pseudo-SARS-CoV-2 entry in bronchial epithelial cells by augmenting cellular cholesterol

Patients with chronic lung disease, obesity, and other co-morbid conditions are at increased risk of severe illness and death when infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Hypercapnia, the elevation of CO(2) in blood and tissue, commonly occurs in patients with sev...

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Detalles Bibliográficos
Autores principales: Chen, Fei, Matsuda, Aiko, Budinger, G. R. Scott, Sporn, Peter H. S., Casalino-Matsuda, S. Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600497/
https://www.ncbi.nlm.nih.gov/pubmed/37901225
http://dx.doi.org/10.3389/fimmu.2023.1251120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600497/
https://www.ncbi.nlm.nih.gov/pubmed/37901225
http://dx.doi.org/10.3389/fimmu.2023.1251120

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