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A potent and broad‐spectrum neutralizing nanobody for SARS‐CoV‐2 viruses, including all major Omicron strains

SARS‐CoV‐2 viruses are highly transmissible and immune evasive. It is critical to develop broad‐spectrum prophylactic and therapeutic antibodies for potential future pandemics. Here, we used the phage display method to discover nanobodies (Nbs) for neutralizing SARS‐CoV‐2 viruses especially Omicron...

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Detalles Bibliográficos
Autores principales: Yao, Hebang, Wang, Hongyang, Zhang, Zhaoyong, Lu, Yuchi, Zhang, Zhiying, Zhang, Yu, Xiong, Xinyi, Wang, Yanqun, Wang, Zhizhi, Yang, Haitao, Zhao, Jincun, Xu, Wenqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600506/
https://www.ncbi.nlm.nih.gov/pubmed/37901798
http://dx.doi.org/10.1002/mco2.397