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Prostaglandin F(2α) synthase promotes oxaliplatin resistance in colorectal cancer through prostaglandin F(2α)-dependent and F(2α)-independent mechanism
BACKGROUND: Oxaliplatin (Oxa) is the first-line chemotherapy drug for colorectal cancer (CRC), and Oxa resistance is crucial for treatment failure. Prostaglandin F(2α) synthase (PGF(2α)) (PGFS), an enzyme that catalyzes the production of PGF(2α), is involved in the proliferation and growth of a vari...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600807/ https://www.ncbi.nlm.nih.gov/pubmed/37900995 http://dx.doi.org/10.3748/wjg.v29.i39.5452 |