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Prostaglandin F(2α) synthase promotes oxaliplatin resistance in colorectal cancer through prostaglandin F(2α)-dependent and F(2α)-independent mechanism

BACKGROUND: Oxaliplatin (Oxa) is the first-line chemotherapy drug for colorectal cancer (CRC), and Oxa resistance is crucial for treatment failure. Prostaglandin F(2α) synthase (PGF(2α)) (PGFS), an enzyme that catalyzes the production of PGF(2α), is involved in the proliferation and growth of a vari...

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Detalles Bibliográficos
Autores principales:	Wang, Yi-Jun, Xie, Xiao-Li, Liu, Hong-Qun, Tian, Hui, Jiang, Xiao-Yu, Zhang, Jiu-Na, Chen, Sheng-Xiong, Liu, Ting, Wang, Shu-Ling, Zhou, Xue, Jin, Xiao-Xu, Liu, Shi-Mao, Jiang, Hui-Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2023
Materias:	Basic Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600807/ https://www.ncbi.nlm.nih.gov/pubmed/37900995 http://dx.doi.org/10.3748/wjg.v29.i39.5452

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