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The stability of the myelinating oligodendrocyte transcriptome is regulated by the nuclear lamina
Oligodendrocytes are specialized cells that insulate and support axons with their myelin membrane, allowing proper brain function. Here, we identify lamin A/C (LMNA/C) as essential for transcriptional and functional stability of myelinating oligodendrocytes. We show that LMNA/C levels increase with...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600948/ https://www.ncbi.nlm.nih.gov/pubmed/37515770 http://dx.doi.org/10.1016/j.celrep.2023.112848 |