The stability of the myelinating oligodendrocyte transcriptome is regulated by the nuclear lamina

Oligodendrocytes are specialized cells that insulate and support axons with their myelin membrane, allowing proper brain function. Here, we identify lamin A/C (LMNA/C) as essential for transcriptional and functional stability of myelinating oligodendrocytes. We show that LMNA/C levels increase with...

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Detalles Bibliográficos
Autores principales: Pruvost, Mathilde, Patzig, Julia, Yattah, Camila, Selcen, Ipek, Hernandez, Marylens, Park, Hye-Jin, Moyon, Sarah, Liu, Shibo, Morioka, Malia S., Shopland, Lindsay, Al-Dalahmah, Osama, Bendl, Jaroslav, Fullard, John F., Roussos, Panos, Goldman, James, He, Ye, Dupree, Jeffrey L., Casaccia, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600948/
https://www.ncbi.nlm.nih.gov/pubmed/37515770
http://dx.doi.org/10.1016/j.celrep.2023.112848

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