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Convergent QSAR Models for the Prediction of Cruzain Inhibitors

[Image: see text] Chagas disease is a parasitosis caused by Trypanosoma cruzi. Cruzain, the major cysteine protease from T. cruzi, is an excellent therapeutic target in the search for antichagasic drugs. It is important in the role of cell invasion, replication, differentiation, and metabolism of th...

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Detalles Bibliográficos
Autores principales: Gonçalves, Rafael Bello, Ferraz, Witor Ribeiro, Calil, Raisa Ludmila, Scotti, Marcus Tullius, Trossini, Gustavo Henrique Goulart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601054/
https://www.ncbi.nlm.nih.gov/pubmed/37901514
http://dx.doi.org/10.1021/acsomega.3c03376