3-Acetyl-11-keto-β-boswellic Acid-Based Hybrids Alleviate Acetaminophen-Induced Hepatotoxicity in HepG2 by the Regulation of Inflammatory and Oxidative Stress Pathways: An Integrated Approach

[Image: see text] In an effort to develop new compounds for managing drug-induced liver injury, we prepared 23 novel hybrids based on 3-acetyl-11-keto-β-boswellic acid (AKBA) using various biocompatible linkers. A bioguided approach was employed to identify the most promising hybrid. Eight compounds...

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Detalles Bibliográficos
Autores principales: Elgazar, Abdullah A., El-Domany, Ramadan A., Eldehna, Wagdy M., Badria, Farid A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601058/
https://www.ncbi.nlm.nih.gov/pubmed/37901542
http://dx.doi.org/10.1021/acsomega.3c05247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601058/
https://www.ncbi.nlm.nih.gov/pubmed/37901542
http://dx.doi.org/10.1021/acsomega.3c05247

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