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Structure Elucidation and Interaction Dynamics of MefA-MsrD Efflux Proteins in Streptococcus pneumoniae: Impact on Macrolide Susceptibility

[Image: see text] Macrolides are empirically used to treat bacterial community-acquired pneumonia (CAP). Streptococcus pneumoniae, being the major pathogen responsible for bacterial CAP with high mortality rates, express MefA-MsrD efflux pumps to hinder macrolide susceptibility. Despite its importan...

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Detalles Bibliográficos
Autores principales: Peela, Sreeram Chandra Murthy, Basu, Soumya, Sharma, Jyoti, AlAsmari, Abdullah F., AlAsmari, Fawaz, Alalmaee, Sultan, Ramaiah, Sudha, Sistla, Sujatha, Livingstone, Paul, Anbarasu, Anand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601061/
https://www.ncbi.nlm.nih.gov/pubmed/37901543
http://dx.doi.org/10.1021/acsomega.3c05210