Arylethynyl- or Alkynyl-Linked Pyrimidine and 7-Deazapurine 2′-Deoxyribonucleoside 3′-Phosphoramidites for Chemical Synthesis of Hypermodified Hydrophobic Oligonucleotides

[Image: see text] We designed and synthesized a set of 2′-deoxyribonucleoside 3′-phosphoramidites derived from 5-phenylethynyluracil, 5-(pentyn-1-yl)cytosine, 7-(indol-3-yl)ethynyl-7-deazaadenine, and 7-isopropylethynyl-7-deazaguanine. These nucleoside phosphoramidites were successfully used for aut...

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Detalles Bibliográficos
Autores principales: Jestřábová, Ivana, Poštová Slavětínská, Lenka, Hocek, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601081/
https://www.ncbi.nlm.nih.gov/pubmed/37901526
http://dx.doi.org/10.1021/acsomega.3c05202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601081/
https://www.ncbi.nlm.nih.gov/pubmed/37901526
http://dx.doi.org/10.1021/acsomega.3c05202

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